POWERFUL ANAPHRO INGREDIENTS
Anaphro supplements are a special mix of herbal extracts and active botanicals that are specially formulated to calm and balance sexual desire.
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Anaphro is made from natural high-quality plant-based ingredients and is available without a prescription. It is non-GMO, vegan, and gluten-free. We’ve listed each individual ingredient below and provided some information on each so you can see what you get with Anaphro.
Anaphro supplements are manufactured in the United States of America in a Good Manufacturing Practice (GMP) compliant facility.
Chasteberry Extract
Licorice Root Extract
Vitex Agnus Castus (scientific name)
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Chasteberry, also called Monk’s pepper or Abraham’s bush, is native to the Holy Land and Mediterranean region. It has long been regarded throughout history as an anaphrodisiac and is called 'chasteberry' for good reason. The Greeks and Romans used it more than 2,000 years ago to subdue or quell the sexual drive. It was used in monasteries during the Middle Ages and also by Buddhist monks. More recent studies indicate that this herb may live up to its name due to the effectiveness of its compounds in reducing testosterone and lowering libido and sexual desire.
Glycyrriza Glabra (scientific name)
Licorice Root is known for its use as flavoring in candies and alcoholic drinks, but it has played an important role in Eastern and Western medicine for centuries. Licorice Root works as a natural anti-androgen containing agents that can work to reduce the amount of testosterone produced in the body which may affect libido. Licorice Root reputedly has a wide range of beneficial nutrients to help the body maintain balance. Licorice Root also contains beneficial antioxidant and anti-inflammatory agents.
Hops Powder Extract
Mother's Wort
Humulus lupulus (scientific name)
Hops are well-known as a major ingredient in beer, but many appreciate the health benefits it offers. Hops has a long history of reducing sexual desire in men. German monks in the 15th century gave hops to young men to help them remain chaste. Modern research has shown that Hops has a calming effect on the nervous system and can help relax muscles. The presence of certain estrogenic constituents purportedly accounts for this plant's traditional anaphrodisiac effect in men.
Leonurus Cardiaca (scientific name)
Leonurus cardiaca means “Liontail heart” which derives from a traditional belief that this herb strengthens the heart and provides a calming effect. Mother's Wort is believed to have an anaphrodisiac effect as well as an effect on reducing anxiety and stress. Mother's Wort has also been associated with long life as one legend has it that the people of a town where a spring ran through a patch of Mother's Wort lived to be over 100 years old.
Skullcap Extract
Reishi
Scutellaria baicalensis (scientific name)
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The name “Skullcap” comes from the helmet-like appearance of the plant’s flowers. Skullcap has been used for thousands of years thanks to it’s effectiveness for treating many ailments. In a double blind study the plant has produced measurable anti-anxiety effects on healthy subjects. It has a reputation for reducing cravings and is used by some for soothing the symptoms of addiction Skullcap has a reputation for “cooling your jets.” Skullcap may have an effect on the hormones in your body as it stimulates the release of endorphins.
Ganoderma lucidum (scientific name)
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Reishi is a mushroom known to have a variety of potential beneficial health effects. Often referred to as "the plant of immortality," it is one of the top medicinal herbs in Eastern medicine. Reishi has long been esteemed for its anaphrodisiac properties. Reishi is regarded as a natural anti-androgen and reportedly prevents the enzyme responsible for testosterone production in the body from achieving its purpose. Reishi also has a reputation for providing other health benefits such as boosting energy, improving prostate health, and promoting better sleep.
Green Tea Extract
Peppermint Extract
Camellia sinensis (scientific name)
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Green Tea is known to promote health throughout the world. Green Tea extract has a wide range of health benefits and there’s evidence that Green Tea might reduce testosterone levels. Various studies have shown Green Tea to inhibit the conversion of testosterone to the more potent androgen. Green Tea has anti-inflammatory properties and helps lower stress and anxiety, which may be beneficial.
Mentha piperita (scientific name)
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Peppermint is a member of the aromatic mint family that has been used throughout history for its varying healing and therapeutic properties. Peppermint leaves have been found in Egyptian pyramids dating back to 1000 B.C., which shows their importance in the ancient world. According to some folk medicine traditions, peppermint is thought to reduce libido. There is research on animals indicating that peppermint may reduce testosterone levels and have an impact on hormonal balance.
REFERENCES
Methodology, References, and Sources
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Long before the emergence of pharmaceutical drugs, people used medicinal plants to alleviate symptoms of numerous ailments. Cultures throughout the world and throughout history used herbs and plants for medicinal purposes. Clearly they were on to something as modern studies have also confirmed their medicinal effects. Today, there's a resurgence in herbal medicines and their powerful chemical elements are the subject of many scientific research studies. Herbal agents are being used for anti-viral, antibacterial, and anti-tumor applications. And now, as an anti-aphrodisiac or an anaphrodisiac.
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Our investigation looked into the effects of herbal medicines and supplementation on calming sexual drive or libido. A multi-year journey led to the development of the powerful herbal supplement, Anaphro.
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Our team consulted with herbologists, formulators, and specialists for research and recommendations for the right formula for Anaphro.
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Research was conducted on a variety of herbs that have been traditionally understood to lower libido. Historical research has shown that through the centuries, certain plants and herbs have been recognized for their use in inhibiting libido. It is estimated that the majority of the world's population still relies on natural phytotherapy (foods, plants, herbs, etc.) as a major source of medicine.
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Some herbal medicines that stood out included Chasteberry, Hops, Licorice, Reishi, Skullcap, Green Tea, and Peppermint, among others.
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A number of herbs and plants were discarded from consideration due to potentially harmful effects or lack of sufficient evidence.
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Our researchers led us to the conclusion that certain herbal medicines may have an lowering or calming effect on the libido. Below is a list of various sources that could help inform the reader in their own research.
Vitex Agnus Castus (Chasteberry)
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Azadbakht, M., Baheddini, A., Shorideh, S., Naser Zadeh, A. (2005). Effect of Vitex Agnus-Castus L. Leaf and Fruit Flavonoidal Extracts on Serum Prolactin Concentration. (Journal of Medicinal Plants. 2005; Volume 4 , Number 16; Page(s) 56 To 61).
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Merz, P.G., Gorkow, C., Schrödter, A., Rietbrock, S., Sieder, C., Loew, D., Dericks-Tan, J.S.E., Taubert, H.D. (1996). The Effects of a Special Agnus Castus Extract (BP1095E1) on Prolactin Secretion in Healthy Male Subjects. (Experimental and Clinical Endocrinology & Diabetes. 1996; 104(6):447–53. DOI: 10.1055/s-0029-1211483).
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Grant, N.N., Anawalt, B.D. (2002). Male Hormonal Contraception: An Update on Research Progress. (Treatments in Endocrinology. August 2002, Volume 1, Issue 4, pp 217–227).
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Webster, D.E., He, Y., Chen, S.N., Pauli, G.F., Farnsworth, N.R., Wang, Z.J. (2011). Opioidergic Mechanisms Underlying the Actions of Vitex Agnus-Castus. (Biochemical Pharmacology, 2011 Jan 1; 81(1): 170–177. DOI: 10.1016/j.bcp.2010.09.013).
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Daniele, C., Thompson Coon, J., Pittler, M.H., Ernst, E. (2005). Vitex Agnus Castus: A Systematic Review of Adverse Events. (Drug Safety. Department of Pharmacology of Natural Substances and General Physiology, University of Rome La Sapienza. 2005; 28(4):319–32).
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Grant, P., Ramasamy, S. (2012). An Update on Plant Derived Anti-Androgens. (International Journal of Endocrinology & Metabolis. 2012 Spring; 10(2): 497–502).
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Nasri, S., Oryan, S., Haeri Rohani, A., Reza Amin, G., (2007). The Effects of Vitex Agnus Castus Extract and its Interaction with Dopaminergic System on LH and Testosterone in Male Mice. (Pakistan Journal of Biological Sciences, 10: 2300-2307. DOI: 10.3923/pjbs.2007.2300.2307).
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Humulus lupulus (Hops)
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Zanolia, P., Zavatti, M., Rivasia, M., Benellib, A., Avallone, R., Baraldi, M. (2009). Experimental Evidence of the Anaphrodisiac Activity of Humulus Lupulus L. in Naïve Male Rats. (Journal of Ethnopharmacology Volume 125, Issue 1, 17 August 2009, Pages 36-4.0 DOI: 10.1016/ j.jep.2009.06.018).
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Farkas K. (1902) About the Physiological Effect of Some Constituents of Hops. [German: Über die physiologische Wirkung einiger Bestandtheile des Hopfens]. European Journal of Physiology. Volume 92, Issue 1-2, 18 September 1902, pp 61-80.
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Koetter, U., Biendl, M. (2010) Hops Humulus lupulus - A Review of its Historic and Medicinal Uses. HerbalGram; American Botanical Council. 2010-08-01.
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Milligan, S.R., Kalita, J.C., Pocock, V., Van De Kauter, V., Stevens, J.F., Deinzer, M.L., Rong, H., De Keukeleire, D. (2000). The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids. (Journal of Endocrinology & Metabolism, Endocrinology and Reproduction Research Group, King's College, 2000 Dec;85(12): 4912-5. DOI: 10.1210/ jcem.85.12.7168).
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Overk, C.R., Yao, P., Chadwick, L.R., Nikolic, D., Sun, Y., Cuendet, M.A., Deng, Y., Hedayat, A.S., Pauli, G.F., Farnsworth, N.R., van Breemen, R.B., Bolton, J.L. (2005). Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). Journal of Agricultural and Food Chemistry. 2005 Aug 10;53(16):6246-53. DOI: 10.1021/jf050448p).
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Wildwood, C., (2003). Mood Enhancing Plants. C.W. Daniel Company LTD, Random House UK. ISBN 97814464899562003.
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American Association for Cancer Research (AACR) (2009). Hops Compound May Prevent Prostate Cancer. Newswise, December 2009.
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Ganoderma lucidum (Reishi)
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Grant, P., Ramasamy, S. (2012). An Update on Plant Derived Anti-Androgens. (International Journal of Endocrinology & Metabolism. 2012 Spring; 10(2): 497-502).
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Nahata, A., Dixit, V. (2012). Ganoderma Lucidum is an Inhibitor of Testosterone-Induced Prostatic Hyperplasia in Rats. (Journal of Andrologia. Vol. 44, May 2012. pp 160-174).
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Fujita, R., Liu, J., Shimizu, K., Konishi, F., Noda, K., Kumamoto, S., Ueda, C., Tajiri, H., Kaneko, S., Suimi, Y., Kondo, R. (2005) Anti-Androgenic Activities of Ganoderma Lucidum. (Journal of Ethnopharmacology, 2005;102(1):107-112. DOI: 10.1016/j.jep.2005.05.041).
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Liu, J., Tamura, S., Kurashiki, K., Shimizu, K., Noda, K., Konishi, F., Kumamoto, S., Kondo, R. (2009) Anti-androgen effects of extracts and compounds from Ganoderma lucidum. (Chemistry & Biodiversity, Feb. 2009 6(2), pp 231-43. DOI: 10.1002/cbdv.200800019).
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Camellia sinensis (Green Tea)
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Chandra, A.K., Choudhury, S.H., De, N., Sarkar, M. (2011). Effect of Green Tea (Camellia sinensis L.) Extract on Morphological and Functional Changes in Adult Male Gonads of Albino Rats. (Indian Journal of Experimental Biology, Vol. 49, September 2011, pp. 689-697).
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Figueiroa, M.S., César, Vieira, J.S., Leite, D.S., Filho, R.C., Ferreira, F., Gouveia, P.S., Udrisar, D.P., Wanderley, M.I. (2009). Green Tea Polyphenols Inhibit Testosterone Production in Rat Leydig Cells. (Asian Journal of Andrology [30 Mar 2009, 11(3):362-370]. DOI: 10.1038/aja.2009.2).
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Kao, Y.H., Hiipakka. R.A., Liao, S. (2000). Modulation of Endocrine Systems and Food Intake by Green Tea Epigallocatechin Gallate. (Endocrinology, Vol. 141, Issue 3, March 2000, pp 980-987. DOI:10.1210/endo.141.3.7368).
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Grant P, Dworakowska D. (2012). Tea and Diabetes: The Laboratory and the Real World. In: Preedy V, editor. (Tea in Health & Disease Prevention. 1st ed. Elsevier Academic Press; 2012).
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Grant, P., Ramasamy, S. (2012). An Update on Plant Derived Anti-Androgens. (International Journal of Endocrinology & Metabolism. 2012 Spring; 10(2): 497-502). Ibid.
Glycyrriza Glabra (Licorice)
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Armanini, D., Bonanni, G., Palermo, M. (1999). Reduction of Serum Testosterone in Men by Licorice. (New England Journal of Medicine, 1999; 341 (15):1158) DOI: 10.1056/NEJM199910073411515).
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Somjen, D., Knoll, E., Vaya, J., Stern, N., Tamir, S. (2004). Estrogen-like Activity of Licorice Root Constituents: Glabridin and Glabrene, in Vascular Tissues in Vitro and in Vivo. (The Journal of Steroid Biochemistry and Molecular Biology. 2004; 91(3):147–55. DOI: 10.1016/j.jsbmb.2004.04.003).
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Armanini, D., Bonanni, G., Mattarello, M.J., Fiore, C., Sartorato, P., Palermo, M. (2003). Licorice Consumption and Serum Testosterone in Healthy Man. (Experimental and Clinical Endocrinology & Diabetes. 2003 Sep;111(6):341-3).
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Tamir, S., Eizenberg, M., Somjen, D., Izrael, S., Vaya, J. (2001). Estrogen-like activity of Glabrene and Other Constituents Isolated from Licorice Root. (The Journal of Steroid Biochemistry and Molecular Biology. 2001;78(3):291–8).
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Grant, P., Ramasamy, S. (2012). An Update on Plant Derived Anti-Androgens. (International Journal of Endocrinology & Metabolism. 2012 Spring; 10(2): 497–502. Ibid).
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Bahmani, M., Rafieian Kopaei, M., Jelodari, M., Eftekhari, Z., Delfan, B., Zargaran, .,Forouzan, S. (2014). A Review of the Health Effects and Uses of Drugs of Plant Licorice (Glycyrrhiza glabra L.) in Iran. (Asian Pacific Journal of Tropical Disease, DOI: 10.1016/S2222-1808(14)60742-8).
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Armanini, D., Mattarello, M.J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., Palermo, M., (2004) . Licorice Reduces Serum Testosterone in Healthy Women. (Steroids, University of Padua. Italy 2004 Oct-Nov;69 (11-12):763-6).
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Bone, K. (2005) Licorice and testosterone revisited. (Townsend Letter: Examiner of Alternative Medicine, Aug/Sept 2005, (abst) #265/266 p 50).
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Kambara, T., Zhou, Y., Kawashima, Y., Kishida, N., Mizutani, K., Ikeda, T., Kameyama, K. (2003). A New Dermatological Availability of the Flavonoid Fraction from Licorice Root. (Journal of Society of Cosmetic Chemists of Japan, 2003 Volume 37 Issue 3 Pages 179-186). S
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Bergner, P. (2014) Glycyrrhiza: Licorice Root and Testosterone. (Medical Herbalism Journal. 11(3):11-12).
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Josephs, R.A., Guinn, J.S., Harper, M.L., Askari, F. (2001). Liquorice consumption and salivary testosterone concentrations. (The Lancet. Volume 358, ISSUE 9293, P1613-1614, November 10, 2001(9293):1613-4).
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Sakamoto, K., Wakabayashi K.. (1988). Inhibitory Effect of Glycyrrhetinic Acid on Testosterone Production in Rat Gonads. (Endocrinol. Japon. 1988, 35 (2), 333-342.)
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Sannikka, E., Terho, P., Suominen, J., Santti, R. (1983). Testosterone Concentrations in Human Seminal Plasma and Saliva and its Correlation with Non-protein-Bound and Total Testosterone Levels in Serum. (The International Journal of Andrology. 1983 Aug;6 (4):319-30. DOI: 10.1111/j.1365-2605.1983.tb00546)
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Sigurjonsdottir, H.A., Axelson, M., Johannsson, G., Manhem, K., Nystrom, E., Wallerstedt, S. (2006). Liquorice in Moderate Doses Does Not Affect Sex Steroid Hormones of Biological Importance Although the Effect Differs Between the Genders. (Hormone Research. 2006;65(2):106-10.
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Uchiumi, Y., Yamamoto, S, Mizutani, K. (2004). Activity of herbal extracts on the control of sebum secretion. (Fragrance Journal. No. 3, Vol 32, pp 53-57. ISSN:0288-9803).
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cf BBC News (2003.) Liquorice Risk to Men's Sex Life. Reported on 17 September, 2003 See http://news.bbc.co.uk/2/hi/health/3112606.st.
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Mentha piperita (Peppermint)
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Uchiumi, Y., Yamamoto, S, Mizutani, K. (2004). Activity of herbal extracts on the control of sebum secretion. (Fragrance Journal. No. 3, Vol 32, pp 53-57. ISSN:0288-9803)
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Güney, M., Oral, B., Karahanli, N., Tamer, M. (2006). The Effect of Mentha Spicata Labiatae on Uterine Tissue in Rats. (Toxicology and Industrial Health 22(8):343-8 · September 2006, DOI: 10.1177/0748233706071738).
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Akdogan, M., Ozguner, M., Kocak, A., Oncu, M., Cicek, E. (2004). Effects of Peppermint Teas on Plasma Testosterone, Follicle-stimulating Hormone, and Luteinizing Hormone Levels and Testicular Tissue in Rats. (Urology. 2004 Aug; 64(2): 394-8. DOI: 10.1016/j.urology. 2004.03.046)
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Akdogan, M., Tamer, M., Cüre, E., Cüre, M.C., Köroglu, B.K., Delibas, N. (2007). Effect of Spearmint (Mentha spicata Labiatae) Teas on Androgen Levels in Women with Hirsutism. (Phytotherapy Research. 2007 May;21(5):444-7. DOI: 10.1002/ptr.2074).
Scutellaria baicalensis (Skullcap)
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Zha, Q., Yang, J., Cu,i M.Y., Liu, J., Fang, Y., Yan, M., Qiu, W., Shang, H., Xu, Z., Yidiresi, R., Weng, J.K., Pluskal, T., Vigouroux, M., Steuernagel, B., Wei, Y.,Yang, L., Hu, Y., Chen, X.Y., Martin, C. (2019). The Reference Genome Sequence of Scutellaria baicalensis Provides Insights into the Evolution of Wogonin Biosynthesis. (Molecular Plant, April 2019; DOI: 10.1016/j.molp. 2019.04.002).
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Jin, .B.R., Chung, K.S., Kima, H.J., An, H.J. (2019). Chinese Skullcap (Scutellaria baicalensis Georgi) Inhibits Inflammation and Proliferation on Benign Prostatic Hyperplasia in Rats. (Journal of Ethnopharmacology, Volume 235, 10 May 2019, Pages 481-488).
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Leonurus Cardiaca (Mother's Wort)
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Zava, D.T., Dollbaum, C.M., Blen, M. (1998). Estrogen and Progestin Bioactivity of Foods, Herbs, and Spices. (Proceedings of the Society for Experimental Biology and Medicine, 1998, Vol. 217, pp. 369-378.).
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Miao, M.S., Guo, L., Tian, S. (2015). Effect of Motherwort Total Alkaloids on a Testosterone Propionate - Induced Acne: Mouse Model. (The Journal of Animal & Plant Sciences, 25 (3 Suppl. 1 ) 2015 Special Issue Page: 1 - 4).
Please Note: Check with your physician or pharmacist before taking Anaphro. The active ingredients generally have had a safe track record with little or no harmful side effects. Anaphro does not contain stimulants or dangerous chemicals. Nevertheless, nothing is risk free and all products no matter how effective, have the potential of risks and side effects. Anaphrodisiacs are not a cure for sex addiction but may offer limited help in subduing sexual urges. Consult a professional if you need more help.